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The Returns from Arthritis Research Volume 2
The Case Studies
There is increasing pressure for research funders to demonstrate, and seek to maximise, the payback from the research they fund. This report, prepared for and funded by the Arthritis Research Campaign (arc), presents the results of an evaluation of 16 research grants awarded by arc in the early 1990s. The main objective was to develop a system for evaluating arthritis research, with a view to allowing arc to stimulate and manage the exploitation of research advances so that they translate into outcomes of practical benefit to people with arthritis.
Volume 2 of the report presents a collection of the case studies used in the study. These case studies all follow a similar format based on the conceptual model and provide a rich and detailed narrative on the payback of each research grant.
Volume 1 of the report presents a framework that conceptualises the relationship between research inputs, process, output and outcomes. Using this framework, we catalogue a diverse range of research output and outcomes arising from these 16 grants and make a series of quantitative and qualitative assessments comparing, for example, payback from project grants versus programme grants. In conclusion, we make six observations:
- There is a diversity of research payback.
- The researcher is the key driver of research translation.
- Short, focused project grants seem to provide value for money.
- Intended and unintended flexibility in funding is used advantageously.
- Referees’ contributions to the peer-review process are of variable benefit.
- The payback framework could be operationalised and embedded by arc.
See Also:
Research BriefResearch Brief
Volume 1
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Contents
Chapter One:
Introduction
Chapter Two:
Case Study A: Back Pain in Primary Care — Assessment of Exercise-Based Management
Chapter Three:
Case Study B: Occupational Activity and Hip Osteoarthritis — A Case Control Study
Chapter Four:
Case Study C: A Comparison of the Tissue Inhibitors of Metalloproteases TIMPs 1 and 2 by Biochemical and Biological Approaches
Chapter Five:
Case Study E: Osteoarthritis of the Knee Joint — Risk Factors, Process and Outcome
Chapter Six:
Case Study F: The Molecular and Cell Biology of Collagen X and Its Relation to Human Disease
Chapter Seven:
Case Study G: Interaction between Complement, Immune Complexes and the Mononuclear Phagocytic System
Chapter Eight:
Case Study H: Lymphocyte Differentiation and Function in Rheumatoid Arthritis
Chapter Nine:
Case Study I: The Pathophysiology of Muscle in Osteoarthritis
Chapter Ten:
Case Study J: Proprioceptive Rehabilitation of the Anterior Cruciate Ligament Deficient Patient
Chapter Eleven:
Case Study K: A Prospective Randomised Theraputic Trial of Lowdose Aspirin Versus Aspirin Plus Low-Dose Subcutaneous Heparin
Chapter Twelve:
Case Study L: The Kennedy Institute Core Grant
Chapter Thirteen:
Case Study M: Mapping and Characterisation of the Genes Involved in Rheumatoid Arthritis
Chapter Fourteen:
Case Study N: The Kennedy Institute Core Grant
Chapter Fifteen:
Case Study O: Identification of Non-HLA Rheumatoid Arthritis Susceptibility Gene
Chapter Sixteen:
Case Study P: The Norfolk Arthritis Register (NOAR)
Appendix A:
Bibliometrics Results Tables
Appendix B:
Assessors’ Report Form
The research described in this report was prepared for and funded by the Arthritis Research Campaign (arc) and performed by RAND Europe.
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